When you’re having a bad day, consider the teratogenic effects of the Veratrum alkaloid, cyclopamine. Scientists say that an attempt to understand sodium channel openers, in and of itself, may produce similar effects. The Cardiovascular Toxicity of Plant Sodium Channel Openers Mad Honey, Cyclopic Ruminants, Sneezing Powder, and Herbal Death Grayanotoxins, Veratrum Alkaloids, and Aconitum […]
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Tox and Hound – Fear and Loathing in Alcohol Withdrawal
by Jeff Lapoint “I was not proud of what I had learned, but I never doubted that it was worth knowing.” Hunter S. Thompson I don’t know why I’ve been identifying with the works of Hunter S Thompson of late. It’s not because the political times seem eerily similar to that of 1972, nor because […]
Tox and Hound – A Few Days on the Drug Circuit
by Jeanna Marraffa A 45-year-old male with history of cardiomyopathy has an out of hospital cardiac arrest. Resuscitative efforts were initiated pre-hospital and return of spontaneous circulation (ROSC) was achieved. However, upon arrival to the emergency department (ED), he was profoundly hypotensive with a blood pressure of 50/palp and a heart rate of 40 beats […]
The Purge
by Howard Greller An absurdists’ take on whole bowel irrigation Throw out your conceited opinions, for it is impossible for a person to begin to learn what he thinks he already knows. – Epictetus, Discourses, 2.17.1 A consensus means that everyone agrees to say collectively what no one believes individually. – Abba […]
Tox & Hound – Illbutrin
by Dan Rusyniak Let me just get this out of the way, I hate bupropion (Wellbutrin™ ) with the “white-hot intensity of a thousand suns” (Hulu). There is nothing “Well” about this drug. It was first synthesized by Burroughs-Wellcome (no, you are not Wellcome) in 1966, and was first approved by the […]