by Jon Cole and Meghan Spyres Jon: Meghan, thank you for joining me on this post. I’ve wanted to write about the logistics of high dose insulin (HDI) for some time now, but I have a lot of my own biases about where insulin belongs in the ordering of our therapies for sick cardiotoxic overdoses […]
Tox and Hound – Talking Back to a Talking Antidote
By Andrew Stolbach Author’s note: I sat down to discuss the role of the out-of-hospital naloxone administration with Evzio® (Kaleo Pharmaceuticals), the world’s only talking naloxone auto-injector. Our interview is presented below in its entirety. AS: Thanks for coming today. Evzio®: To Inject. Place black end against outer thigh. Then press firmly. 5, 4, 3, […]
Tox and Hound – A Happy New Year To All!
7 Cyanide Wishes and Thallium Dreams! Howard – The story of the year? The Tox and The Hound! Toxicology’s foray into the world of FOAM has had an auspicious start. I am obviously biased, but I think that we have a phenomenal team and have put forth some outstanding content. From toxicology·fundamentals, to the classics (including […]
Tox and Hound – Enter Clonidine
by Sarah Shafer As promised in my last post, where I discussed the utility of naloxone in clonidine overdose, we’re going to spend some time today talking about clonidine in opioid withdrawal. Is it a useful therapy for treating opioid withdrawal, or like Claudius in Hamlet, a gaslighting distractor? Before we dive in, let me […]