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The Tox and the Hound

Toxicologists Writing About Toxicology

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Tox & Hound – MALA-ficence

January 15, 2020 by Tox & Hound 50 Comments

Predicting Outcome in Metformin Lactic Acidosis by Diane Calello A 56-year-old male with diabetes and hepatitis comes in after an intentional overdose of his own metformin. On evaluation, he is awake and alert but mildly tachycardic. Lab evaluation demonstrates elevated lactate at 4 mmol/L and a pH of 7.3. Will he die? Metformin is one […]

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