A very special welcome to our newest hound, Dr. Trevonne Thompson! You can learn more about him here . . . by Trevonne Thompson Archery should be recognized as the official sport of medical toxicology. Medical Toxicology is, by my own estimation, an avant-garde specialty, and is arguably the best specialty in medicine. While its modern history, […]
Tox and Hound – A Few Days on the Drug Circuit
by Jeanna Marraffa A 45-year-old male with history of cardiomyopathy has an out of hospital cardiac arrest. Resuscitative efforts were initiated pre-hospital and return of spontaneous circulation (ROSC) was achieved. However, upon arrival to the emergency department (ED), he was profoundly hypotensive with a blood pressure of 50/palp and a heart rate of 40 beats […]
Tox and Hound – In the Beginning
by Diane Calello Risk Assessment in Acetaminophen Toxicity In the beginning God created the heavens and the earth. Darkness covered the formless earth, wind swept over the waters. And God said, “Let there be acetaminophen”. And so it was. And it was good. Then man discovered acetaminophen and, realizing he was naked without it, covered […]
Tox and Hound – Sneaking into the Party
by Sarah Shafer How does a heart break? In the case of beta-blocker (BB) and calcium-channel blocker (CCB) overdose, it’s a lack of calcium. Calcium is essential to muscle contraction, allowing actin and myosin to interact so that the cell shortens. Without calcium, the myosin and actin are blocked from interacting, and the cell stays […]
Tox and Hound – Check Yourself
by Andrew Stolbach The history of cancer therapy is entwined with the history of the 20th and 21st centuries. Scientific discovery does not occur in a historical vacuum. The swirl of world events does not stop outside the laboratory. In 1910, as Viennese researchers Ernest Freund and Gisa Kaminer published observations that some substance in […]
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