by Dan Rusyniak When Gwyneth Paltrow “consciously uncoupled” from Chris Martin, I immediately thought of mitochondria. Why mitochondria? For one because mitochondria are the favorite organelle of toxicologists (sorry, sarcoplasmic reticulum . . .). And second, because I am fascinated by drugs that uncouple oxidative phosphorylation. There are lots of toxins that target mitochondria. There […]
Tox and Hound – Fellow Friday – Drug and Toxin-Induced Hepatic Microvesicular Steatosis
Drug and Toxin-Induced Hepatic Microvesicular Steatosis From Captain Bligh to Bacillus cereus by Steven Curry, M.D. Department of Medical Toxicology Banner – University Medical Center Phoenix @SteveCurryMD Drug and toxin-induced liver diseases comprise various histologic patterns. A few examples a toxicologist may encounter include perisinusoidal fibrosis with hypervitaminosis A, peliosis hepatis from sex steroids, veno-occlusive […]