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The Tox and the Hound

Toxicologists Writing About Toxicology

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Tox and Hound – Great! Naloxone worked! Now what?

November 4, 2019 by Tox & Hound 4 Comments

by Jon Cole In some ways, you never outgrow your training. Before my medical toxicology fellowship, I completed a residency in emergency medicine. It is my primary specialty and practice, and it’s by far the most common place I encounter most of the patients I see. As opioids have become the primary cause of poisoning […]

Tox and Hound – Talking Back to a Talking Antidote

February 18, 2019 by Tox & Hound Leave a Comment

By Andrew Stolbach Author’s note: I sat down to discuss the role of the out-of-hospital naloxone administration with Evzio® (Kaleo Pharmaceuticals), the world’s only talking naloxone auto-injector. Our interview is presented below in its entirety. AS: Thanks for coming today. Evzio®: To Inject. Place black end against outer thigh. Then press firmly. 5, 4, 3, […]

Tox and Hound – Narcan’t

August 28, 2018 by Tox & Hound 4 Comments

by Sarah Shafer     You’re taking care of a 4-year-old who got into some medication. His pupils are small, his heart rate is slow, and he’s more drowsy than a resident at a late night party. Toxidrome fluent, you give him a slug of naloxone . . . and . . . nothing happens. […]

The Tox & The Hound – IS THIS ANYTHING?

April 30, 2018 by Tox & Hound 13 Comments

by Andrew Stolbach       Naloxone-resistant opioids I just read another paper about someone not waking up with naloxone after taking a synthetic opioid. The prospect of “narcan-resistant” opioids makes me think of David Letterman. When I was in elementary school I used to watch David Letterman’s show with my mother after school. This […]

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