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The Tox and the Hound

Toxicologists Writing About Toxicology

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Tox and Hound – Unconscious Uncoupling – Managing pH in Salicylate Overdoses

April 30, 2019 by Tox & Hound 3 Comments

by Dan Rusyniak When Gwyneth Paltrow “consciously uncoupled” from Chris Martin, I immediately thought of mitochondria. Why mitochondria? For one because mitochondria are the favorite organelle of toxicologists (sorry, sarcoplasmic reticulum . . .). And second, because I am fascinated by drugs that uncouple oxidative phosphorylation. There are lots of toxins that target mitochondria. There […]

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