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The Tox and the Hound

Toxicologists Writing About Toxicology

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The Dantastic Mr. Tox & Howard – S03E03 – Inside Out

July 6, 2020 by Tox & Hound 2 Comments

Ingestible electronic systems, Mario and Luigi’s new digs, and human energy harvesting with Dr. Peter Chai. We’re back! Join Dan (@drusyniak) &Howard (@heshiegreshie) as they explore the GI tract of the city, build a career of excrement, and determine which bathroom is the cleanest with Dr. Peter Chai (@PeterRchai). We hope that everyone stays safe, […]

Tox and Hound – Love and Half-Life*

February 26, 2020 by Tox & Hound 1 Comment

by Sarah Shafer *Not the video game I’ve gotten some version of this call many times in my budding career as a medical toxicologist: “Hello, we have a something-year-old patient in the ER who overdosed on ______ (fill in the blank) medication. How long do we need to watch them before we can medically clear […]

Tox and Hound – One Therapy To Rule Them All? Sugar vs Squeeze in Cardiotoxic Poisoning

February 18, 2020 by Tox & Hound 2 Comments

by Jon Cole and Meghan Spyres Jon: Meghan, thank you for joining me on this post. I’ve wanted to write about the logistics of high dose insulin (HDI) for some time now, but I have a lot of my own biases about where insulin belongs in the ordering of our therapies for sick cardiotoxic overdoses […]

Tox & Hound – A Toxicological Brain Teaser. The Complexities of Valproic Acid Metabolism.

February 4, 2020 by Tox & Hound 2 Comments

by Christine Murphy What do you think about when you hear the words “drug toxicity”? Do you think about a patient who overdosed or someone who is experiencing a toxic side effect from a medication? A lot of times, the answer might depend on what we remember about a drug when we hear the name. […]

“B-Sides” in Analgesia

January 23, 2020 by Tox & Hound 22 Comments

by Meghan Spyres Ketamine was gifted to the world as a result of investigations into its evil older brother: phencyclidine (PCP). PCP, commonly known as ‘angel dust’ (quite the misnomer, Urban Dictionary suggests the use of the more fitting ‘devil dust’. . .) was initially used as a pharmaceutical in the 1950s under trade name […]

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